How Long Does It Take NexGard to Start Working: A Comprehensive Guide

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Have you recently started using NexGard to protect your furry friend from fleas and ticks? If so, you might be wondering how long it takes for NexGard to start working. Understanding the onset of action is crucial for ensuring your pet’s safety and well-being. In this article, we’ll delve into the details and provide you with all the information you need to know about the effectiveness of NexGard.

Understanding NexGard

NexGard is a popular oral flea and tick treatment for dogs. It is formulated with a powerful active ingredient called afoxolaner, which belongs to the isoxazoline class of drugs. This ingredient specifically targets the nervous system of fleas and ticks, ultimately leading to their demise. Unlike topical treatments, NexGard is administered orally, making it a convenient option for pet owners.

NexGard is highly effective in preventing and treating flea and tick infestations. It not only kills existing fleas and ticks but also provides a month-long protection against future infestations. This makes NexGard an excellent choice for pet owners looking for a long-lasting solution to keep their furry companions safe.

Factors Affecting NexGard’s Effectiveness

Several factors can influence how long it takes for NexGard to start working. Let’s take a closer look at these factors:

1. Pet’s Weight

The weight of your pet plays a significant role in how NexGard is absorbed and distributed throughout their body. Generally, heavier dogs may require a higher dosage to ensure optimal effectiveness. It’s essential to follow the recommended dosage guidelines provided by your veterinarian to achieve the best results.

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2. Pet’s Metabolism

Every pet has a unique metabolism, which affects how quickly NexGard is metabolized and starts working. If your furry friend has a faster metabolism, the onset of action may be quicker. Conversely, a slower metabolism might lead to a slightly delayed response. It’s important to be patient and allow NexGard sufficient time to take effect.

3. Pet’s Overall Health

The overall health of your pet can impact how quickly NexGard starts working. Pets with underlying health conditions or weakened immune systems may experience a delayed response. It’s crucial to ensure your pet is in good health before administering NexGard. If you have any concerns, consult your veterinarian for guidance.

How Long Does NexGard Take to Start Working?

The time it takes for NexGard to start working can vary from pet to pet. While some dogs may experience immediate relief, others might require a little more time. Generally, NexGard begins working within a few hours of administration, with visible results seen within 24 hours.

It’s important to note that NexGard is not an instant solution. It needs time to be absorbed by your pet’s body and distributed throughout their system to effectively eliminate fleas and ticks. Therefore, consistency and adherence to the recommended monthly dosage are crucial to ensure continuous protection.

Frequently Asked Questions (FAQs)

Can NexGard start working immediately?

While NexGard starts working soon after administration, it may not provide immediate relief. It takes some time for the active ingredient to take effect and eliminate fleas and ticks. Be patient and allow NexGard to work its magic within the expected timeframe.

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What should I do if NexGard doesn’t work within the expected timeframe?

If you notice that NexGard is not working as expected, it’s important to consult your veterinarian. They can assess your pet’s condition and provide guidance on the appropriate steps to take. Remember, each pet is unique, and their response to NexGard can vary.


In conclusion, NexGard is an effective and convenient solution for protecting your furry friend from fleas and ticks. Understanding how long it takes NexGard to start working is essential for ensuring the well-being of your pet. Factors such as weight, metabolism, and overall health can influence the onset of action. While NexGard typically begins working within a few hours, it’s important to give it time to show its full effectiveness. Remember to follow the recommended dosage and consult your veterinarian for any concerns or questions. With NexGard, you can provide your pet with the protection they need for a happy and healthy life.

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